For years after it received FDA-approval in 2002, Botox was the only name in the game for softening the appearance of crow’s feet, frown lines and forehead wrinkles. Even now, with a growing number of competitors to challenge its reign — including Dysport, Jeuveau, Xeomin and Daxxify — Botox is still (incorrectly) used to refer to any type of injectable neuromodulator, in the same way that all slow cookers are often called “Crockpots,” regardless of brand.
At Gifted Medspa, a new FDA-approved neuromodulator is joining the list of Botox competitors: Letybo, the leading anti-wrinkle injectable in South Korea that’s making waves in the U.S. With a proven track record of safety and use overseas, Letybo gives patients more options than ever when it comes to reducing the appearance of those pesky expression lines and wrinkles.
What Is Letybo?
Letybo — manufactured by Hugel, a global leader in medical aesthetics — is the newest FDA-approved neuromodulator for treating frown lines (11s between the brows). It can also be used off-label to treat areas around the eyes, forehead and mouth. Letybo is formulated with botulinum toxin type A (letibotulinumtoxinA) and works by temporarily relaxing the facial muscles, allowing the skin to stay smooth and unwrinkled when you laugh, wink or smile.
Letybo is the most popular neuromodulator in South Korea, where it is better known by its brand name: Botulax. It’s been around for over a decade and is often combined with dermal fillers, hydration boosters and facials in a single visit for visibly improved and healthier-looking skin.
How Does Letybo Work?
Letybo works similarly to Botox, Dysport and other brands you might be more familiar with. When injected into targeted areas, it temporarily blocks the release of a neurotransmitter that tells the muscles to contract. Treated muscles relax, allowing the overlying skin to smooth, effectively reducing the appearance of expression lines and wrinkles for three to five months.
Who Is Hugel?
Hugel is a global leader in the medical aesthetics industry. Established in 2001, Hugel specializes in injectables that rejuvenate and refresh the skin, including neuromodulators, dermal fillers and skin boosters, as well as absorbable threads and skincare products. Hugel is a household name in South Korea and the only South Korean company with regulatory approvals in the world’s three largest neuromodulator markets — the U.S., China and Europe. Hugel has a long track record of safety and quality and is committed to advancing the medical aesthetics field through continued research, new technology and comprehensive training.
The Benefits of Letybo
Letybo provides a fresh option for patients looking to reduce expression lines and wrinkles with proven technology. This innovative treatment offers several distinct advantages for those seeking facial rejuvenation.
Effectively Reduces Expression Lines
Letybo excels at softening dynamic wrinkles that form from repetitive facial movements like laughing, squinting and smiling. The treatment targets the 11s between brows, forehead wrinkles and crow’s feet with precision. By temporarily relaxing the underlying muscles, Letybo allows the skin to remain smooth even when you’re expressing yourself, giving you a more refreshed appearance without looking frozen or unnatural.
Helps Prevent New Wrinkles
Beyond addressing existing lines, neuromodulators like Letybo work proactively to help prevent new wrinkles from forming. By limiting the repeated muscle movements that eventually lead to permanent creases, regular treatments can keep your skin smoother for longer. This preventive approach is especially beneficial for younger patients who want to maintain their youthful look or for those with the early signs of aging who want to stay ahead of more noticeable changes.
Quick Treatment With Zero Downtime
Letybo treatments typically take just 10-15 minutes, making them perfect for busy schedules. You can stop by during your lunch break and return to work immediately after. There’s no recovery period needed — you might experience minor redness at injection sites, but this fades within an hour. Results develop gradually over the following days, providing a natural-looking transformation that won’t leave others wondering if you’ve “had work done.”
Is Letybo Right for Me?
Letybo is ideal for most patients who want to soften the appearance of facial wrinkles caused by repetitive muscle movements. It is safe and effective for both men and women, delivering long-lasting results that develop after just a few days. As with all anti-wrinkle injectables, candidates should have realistic goals and expectations. If you’re interested in the newest generation of neuromodulators, Letybo may become your new favorite treatment if you:
- Prefer minimally invasive treatments with no downtime
- Want to reduce the appearance of crow’s feet, forehead wrinkles and frown lines
- Have developed a resistance to Botox
- Want more choices when it comes to anti-wrinkle injections
- Are excited to try the newest FDA-approved neuromodulator
At Gifted Medspa, our experienced injectors — Anna Ciccolini, PA-C and Darren Ciccolini, PA-C — will evaluate your needs and concerns to determine if Letybo is right for you. They will also develop a personalized treatment plan just for you and may recommend a combination approach to help you achieve your aesthetic goals!
What to Expect During Your Letybo Treatment
Before
Your Letybo journey begins with a comprehensive consultation with one of our expert injectors. We’ll discuss your aesthetic goals, evaluate your facial anatomy and review your medical history to ensure Letybo is right for you. We may also recommend avoiding blood-thinning medications like aspirin and ibuprofen for a few days before treatment to minimize bruising. Come to your appointment with a clean face, free of makeup, for the best results.
During
The treatment itself is quick and straightforward. One of our skilled providers will cleanse the treatment area and may apply a topical numbing cream, if desired. Then, we will inject small amounts of Letybo into specific facial muscles using an ultra-fine needle. Most patients describe the sensation as a brief pinch, less painful than you might expect. The entire process typically takes about 10-15 minutes to complete, depending on how many areas you’re treating.
After
After your Letybo treatment, you can return to your normal activities immediately. We recommend avoiding strenuous exercise, alcohol and excessive heat (like saunas or hot tubs) for 24 hours. You should also remain upright for at least four hours and avoid touching or massaging the treated areas. Some patients experience minor redness, swelling or bruising at the injection sites, but these side effects resolve quickly and can be covered with makeup.
Letybo Results
Letybo results develop gradually over the first week after treatment, with most patients noticing initial improvements within two to three days and optimal results after about seven to 14 days. Your refreshed, smoother appearance can last for three to five months, depending on your metabolism and the areas treated. As the product naturally breaks down over time, muscle movement gradually returns. Regular maintenance or touch-up treatments (typically scheduled every three to four months) can help extend and enhance your results long-term!
Why Choose Gifted Medspa for Letybo?
At Gifted Medspa, our approach to Letybo and all aesthetic treatments is driven by our commitment to excellence and personalized care. When you choose us for your Letybo treatment, you benefit from:
- Expert Injectors — Our providers, Anna Ciccolini, PA-C and Darren Ciccolini, PA-C, bring decades of combined medical experience to every treatment. Their extensive knowledge of facial anatomy, advanced injection techniques and artistic eye ensure precise, natural-looking results that enhance your unique features.
- A Customized Approach — We understand that no two faces are alike. Your Letybo treatment will be tailored specifically to your facial structure, muscle patterns and aesthetic goals. This personalized approach delivers results that look natural and balanced, never overdone or frozen.
- Comprehensive Care — From your initial consultation through your follow-up care, we provide attentive service and detailed guidance every step of the way. We take the time to answer all your questions, set realistic expectations and ensure your complete comfort throughout the treatment process.
Book a consultation today and discover why our patients trust Gifted Medspa with their aesthetic care. Call us at 919-300-8308 or schedule online through our convenient booking system.
“My experience with Anna was nothing short of amazing! She’s incredibly professional and truly listens to any concerns or medical needs. From the moment you step into her calming, welcoming space, you know you’re in good hands. Every visit feels personalized, and she’s great at adapting treatments based on my needs.”
— Annie F.
Experience the Letybo Difference at Gifted Medspa
Ready to discover what South Korea’s favorite neuromodulator can do for you? Schedule a consultation with our expert injectors today! At Gifted Medspa in Cary, NC, we pride ourselves on offering the latest innovations in aesthetics with the personalized care you deserve. Contact us at 919-300-8308 or book online to be among the first to experience the Letybo advantage.
Frequently Asked Questions
How Does Letybo Differ From Other Neuromodulators?
In many ways, Letybo doesn’t differ much from neuromodulators like Botox or Dysport — they all work equally as well in reducing the appearance of expression lines. However, some patients may notice subtle differences from brand to brand, finding they prefer one over the other. Those who develop Botox resistance may also benefit from Letybo, as it contains fewer of the complexing proteins that can trigger the production of antibodies and cause it to stop working.
Is Letybo Reversible?
Unlike fillers, which can be dissolved with an enzyme, Letybo and other neuromodulators cannot be immediately reversed once injected. However, Letybo’s effects are temporary by nature, typically lasting for three to five months as the product gradually breaks down. If you’re trying Letybo for the first time, we recommend starting with a conservative approach that can be adjusted at follow-up appointments based on your results.
Can Letybo Be Used for Men?
Yes! Letybo is absolutely suitable for both men and women who want to soften the appearance of dynamic wrinkles and achieve a refreshed, youthful look. Our expert injectors customize each treatment based on your unique facial structure, muscle mass and aesthetic goals, ensuring natural-looking results that preserve masculine features while reducing unwanted lines.
Is Letybo Safe for All Skin Types?
Letybo is safe and effective for all skin types and tones, with no increased risk of pigmentation issues or adverse reactions based on skin color. It works by targeting facial muscles rather than the skin itself, making it equally suitable for everyone. At Gifted Medspa, we treat a diverse clientele and tailor each treatment to your individual needs and concerns.
How Soon Will My Results “Kick In?”
Most patients begin to notice initial changes within two to three days of treatment, with results continuing to develop over the following week. Full results are typically visible by days seven to 14. This timeline is similar to other neuromodulators, though individual experiences may vary. For special events, we recommend scheduling your treatment at least two weeks in advance.
